About ISS


The Infantile Seizure Society (ISS) is a professional organization which was born in Japan in 1998, with a specific aim of promoting clinical and basic research on seizures in early life. The members are composed of pediatric epileptologists worldwide; it will hold a scientific meeting (International Symposia since 2001) once a year with a main theme of compelling importance.

Yukio Fukuyama, 1928 – 2014

It is with great sadness that we announce the death of Professor Yukio Fukuyama, a true pioneer in the field of pediatric neurology who chaired our Department of Pediatrics at Tokyo Women’ s Medical University, for a quarter of a century, teaching and mentoring young doctors and leading us into the 21st century. The depth and breadth of his accomplishments are a testament to his commitment to patients, their families, the university, his coworkers and advances in pediatric neurology worldwide. He will be sorely missed by friends and colleagues alike, thanks to his tireless efforts to advance Child Neurology, always based on his belief in “slow but steady” progress.

Professor Fukuyama (DOB: 28 May, 1928, Birthplace: Miyazaki, Japan) passed away on July 17, 2014, due to aspiration pneumonia, at the age of 86.

Most Recent Positions:

  • Emeritus Professor, Tokyo Women’ s Medical University, Tokyo
  • Honorary Chairman, Board of Trustees, Japanese Society of Child Neurology
  • Honorary President, Asian & Oceanian Child Neurology Association
  • Honorary Chairman of Infantile Seizure Society

Major Fields of Interest:

Child neurology, with emphasis on pediatric epileptology, pediatric neuro-muscular disorders, clinical neurogenetics, international relations
Honorary Memberships in Academic Societies:

  • Honorary Chairman, Board of Trustees, Japanese Society of Child Neurology (since 1993)
  • Honorary President, Asian & Oceanian Child Neurology Association (since 1992)
  • Honorary Chairman, Infantile Seizure Society (since 2013)
  • Honorary Member of the following societies:
  • American Academy of Neurology (since 1990)
  • American Neurological Association (since 2006)
  • Canadian Child Neurology Society (since 1985)
  • Child Neurology Society (US) (since 1986)
  • European Paediatric Neurology Society (since 2005)
  • International Child Neurology Association (since 2010)
  • Japan Epilepsy Society (since 1998)
  • Japan Pediatric Society (since 1999)
  • Japanese Society of Neurology (since 2000)
  • Japanese Society of Clinical Neurophysiology (since 1995)
  • Japanese Society of Human Genetics (since 1999)
  • Japan Teratology Society (since 1998)
  • Philippine Child Neurology Society (since 2008)

Active Member of the Following Societies:

  • American Association for the Advancement of Science
  • American Epilepsy Society
  • American Society of Human Genetics
  • Corresponding Member of the: Societe Europeenne de Neurologie Pediatrique (since 2002)
  • 4th President, International Child Neurology Association (1982-1986)
  • President, The Joint Meeting of the 5th International Child Neurology Congress and the 3rd Asian & Oceanian Congress of Child Neurology, Tokyo, November 1990.
  • President, Infantile Seizure Society (1998-2001, 2005-2012)


  • University: Faculty of Medicine, University of Tokyo, 1948-1952
  • Internship: University of Tokyo Hospital, Tokyo, 1952-1953
  • Postgraduate: Postgraduate Course, Faculty of Medicine,
  • University of Tokyo, Tokyo, 1954-1957
  • Doctorate: University of Tokyo, 1957
  • Diploma of Medicine: University of Tokyo, 1959


  • Clinical Associate: Department of Pediatrics, University of Tokyo, 1957-1960
  • Assistant Professor: (same) 1960-1964
  • Associate Professor: (same) 1964-1965
  • Chief Pediatrician: National Children’ s Hospital, Tokyo, 1965-1967
  • Professor & Chairman: Tokyo Women’ s Medical College, Tokyo, 1967-1994
  • Guest Professor: Department of Pediatrics, Saitama Medical University, Saitama, 1994-1999
  • Emeritus Professor: Tokyo Women’ s Medical University, Tokyo 1994-present
  • Director: Child Neurology Institute, Tokyo 1994-present
  • President: Infantile Seizure Society, Tokyo 1998-present


  • Kimura Taro Prize, Japanese Epilepsy Association (1989)
  • Frank Ford Lectureship Award, International Child Neurology Association (1992)
  • Achievement Award, Japan Epilepsy Research Foundation (1993)
  • Bronze Medal, Societa Italiana di Neuropediatria (1996)
  • Duchenne-Erb Prize, Deutsche Gesellschaft fur Muskelkranke (1999)
  • Achievement Award, Japanese Society of Human Genetics (1999)
  • Achievement Grand Award, Japan Medical Association (1999)
  • Lifetime Achievement Award, World Federation of Neurology (2002)
  • International Henri Gastaut Prize, French Chapter of the ILAE (2003)
  • The William G. Lennox Award, American Epilepsy Society (2004)
  • Ambassador for Epilepsy Award, ILAE/IBE (2007)
  • The Asahi Award 2007, The Asahi Shimbun Cultural Foundation (2008)
  • Achievement Grand Award, 2008, Japan Pediatric Society (2008)
  • Special Recognition Award, Japanese Society of Child Neurology (2008)
  • The Order of the Sacred Treasure, Gold Rays with Neck Ribbon, The Cabinet Office, Japanese Government (2008)
  • The First Japan Epilepsy Society Outstanding Achievement Award (2010)

Selected List of Books (first-author or editor):

  • Epilepsy. The Clinic and The Research. Igaku Shoin, Tokyo, 1974. 666 pp. (in Japanese)
  • Clinical Aspects of Epilepsy. Tokyo Igaku Publ, Tokyo, 1977. 314 pp. (in Japanese)
  • Child Neurology. Elsevier, Amsterdam, 1982. 419 pp.
  • Epilepsies in Childhood. 2nd ed. Ishiyaku Publ, Tokyo, 1984. 204 pp. (in Japanese)
  • Child Neurology Atlas. Shindan To Chiryo Publ, Tokyo, 1986. 368 pp. (in Japanese)
  • Neurological Examinations in Children. Kanehara Publ, Tokyo. 1987. 324 pp. (in Japanese)
  • EEG and Evoked Potentials in Children. Kanehara Publ, Tokyo, 1990. 369 pp. (in Japanese)
  • Modern Perspectives of Child Neurology. JSCN, Tokyo, 1991. 360 pp.
  • Febrile Seizures -Modern Concept-. Nihon Shoni-iji Publ, Tokyo, 1991. 156 pp. (in Japanese)
  • Fetal and Neonatal Neurology. Elsevier, Amsterdam, 1992. 388 pp.
  • Crossroads of Child Neurology. TWMU, Tokyo, 1995. 728 pp.
  • Congenital Muscular Dystrophies. Elsevier, Amsterdam, 1997. 440 pp.
  • Epilepsy Bibliography ? Books and Monographs. (1945-2003). 8th print ed. Seiwa Shoten: Tokyo, 2004. 234 pp.
  • Biology of Seizure Susceptibility in Developing Brain, John Libbey Eurotext, Montrouge 2008. 231 pp.
  • Epilepsy Bibliography ? Books and Monographs (1945-2009). 10th ed. Online. ILAE website. 2009.

Recent Publications in Journals:

  • Fukuyama Y, ed. West syndrome and other infantile epileptic encephalopathies.Brain & Development 2001; 23(7): 441-769.
  • Fukuyama Y, ed. Chromosomal aberrations and epileptic syndromes. Brain & Development 2005; 27: 79-147 and 358-391.
  • Fukuyama Y, ed. Neuronal migration disorders and childhood epilepsies.J Child Neurol 2005; 20(4): 273-397.
  • Maeda Y, Fukuyama Y, et al. Rasmussen syndrome: Multifocal spread of inflammation suggested from MRI and PET findings. Epilepsia 2003; 44: 1118-1121.
  • Dravet C, Fukuyama Y, et al. Severe myoclonic epilepsy in infancy: Dravet syndrome. Advances in Neurology 2005; 95: 71-102.
  • Oguni H, Fukuyama Y, et al. Severe myoclonic epilepsy in infancy: Clinical analysis and relation to SCN1A mutation in a Japanese cohort. Advances in Neurology 2005; 95: 103-113.
  • Dravet C, Fukuyama Y, et al. Severe myoclonic epilepsy in infancy (Dravet syndrome). In: Roger J, et al. Epileptic syndromes in infancy, childhood and adolescence. 4th Ed. John Libbey Eurotext, Montrouge. 2005: 89-113.
  • Fukuyama Y, Sakauchi M. Syndromes des crises benignes du nourrisson. Epilepsies 2006; 18(1): 8-23.
  • Fukuyama Y, ed. Epileptic syndromes in infancy and early childhood. Epilepsy Res 2006; 70 Supplement: 279 pages.
  • Kato N, Fukuyama Y, et al. Paroxysmal kinesigenic choreoathetosis: From first discovery in 1892 to genetic linkage with benign familial infantile convulsions. Epilepsy Res 2006; 70 Suppl: S174-S184.
  • Fukuyama Y, ed. Status epilepticus in infants and young children. Acta Neurol Scand 2007; 115 Suppl 186: 86 pp.
  • Fukuyama Y. History and perspectives of Fukuyama congenital muscular dystrophy research. Brain and Nerve; 2008; 60(1): 43-52.
  • Fukuyama Y. Japanese activities in epileptology assessed from an international viewpoint ? On the occasion of winning the ILAE/IBE Ambassador for Epilepsy Award 2007 -. Tenkan Kenkyu (J Jpn Epilepsy Soc) 2008; 26: 87-93. (in Japanese with English abstract)
  • Fukuyama Y, Takahashi T, Hirose S, Takeuchi Y, guest editors. Febrile seizures and related conditions. Special sections I and II. Brain & Development 2009; 31(5): 358-404; Brain & Development 2010; 32(1): 33-77.
  • Fukuyama Y, Takahashi T, Hirose S, Matsuishi T, guest editors. Epilepsy in autism spectrum disorders and related conditions. Brain & Development 2010; 32(9): 708-789.